Hormones and the Role They Play in Menopause

Hormones and the Role They Play in Menopause

Why do we have the perimenopause and menopause and what exactly has it got to do with your hormones? Hormones are your body’s communication system, carrying instructions from one set of cells to another. But what role your hormones and endocrine system (the glands that make hormones) play and their impact on your perimenopause and menopause can be confusing. So let’s take a look at some of the basics:

Why Are My Hormones All Over the Place?

During a woman’s reproductive years, the ovaries produce two main hormones: estrogen and progesterone. This happens in a cyclical manner and results in the regular release of eggs and regular periods (or menstrual cycle). As women age, estrogen production by the ovaries declines, leading to changes in the menstrual cycle.

As you enter the perimenopause life stage, women will experience a hormone imbalance due to the fluctuation and then decline of three main hormones that regulate the menstrual cycle, sexual desire and, as research is discovering, many other functions in your body. Reproductive aging is the underlying process driving these hormonal changes. Estrogen, progesterone, and testosterone are all naturally occurring hormones that, when levels go up and down, have a direct effect on the way your body reacts, which leads to perimenopause and menopause symptoms.

These changes typically occur as part of natural menopause, which is a normal aging process, but can also result from medical interventions.

Understanding the Role of Estrogen, Progesterone, and Testosterone

Estrogen

  • Estrogen is a primary female sex hormone. While both men and women produce it, it plays a much more significant role in the female body.
  • Mainly produced by the ovaries, estrogen is essential for puberty, breast development, regulating the menstrual cycle, fertility, supporting pregnancy, maintaining bone strength, and managing cholesterol levels.
  • Estrogen supports brain and heart function, helps protect the skin from aging, and plays a role in bladder control.
  • Estrogen levels fluctuate throughout the menstrual cycle and life stages they are highest around ovulation and lowest during menstruation.

Progesterone

  • Progesterone plays a key role in pregnancy. It is produced by the ovaries after ovulation and prepares the uterus to accept and support a fertilised egg.
  • Progesterone levels fluctuate during the menstrual cycle they are low at the start, rise after ovulation for about five days, then drop again.
  • Progesterone prevents uterine muscle contractions that could reject a fertilised egg, supporting early pregnancy.
  • Progesterone also helps regulate blood pressure, and contributes to better mood and sleep quality.

Testosterone

  • Testosterone is a hormone found in both men and women, but men produce 10–20 times more than women.
  • In women, testosterone is released directly by the ovaries into the bloodstream, where it acts on cells and is also partially converted into estrogen.
  • Testosterone levels peak in women during their 20s, then gradually decline to about 25% of that peak by the time they reach menopause, followed by a slight increase in later years.
  • Low testosterone in women is linked to reduced sex drive and sexual responsiveness, as well as lower energy levels, decreased muscle mass, and impaired brain function.

What’s Really Happening With Your Hormones in Perimenopause and Menopause?

Up to 10 years before menopause you may experience subtle (or not so subtle!) hormonal changes. This is the perimenopause period. One of the most obvious signs, although not always the first, is a disruption in your periods when they might become less regular, shorter, longer and have a different flow. Abnormal vaginal bleeding during perimenopause or after menopause should be evaluated by a healthcare professional.

All the way through perimenopause your hormone levels can fluctuate from day to day and week to week. As well as disrupted periods, these yo-yoing hormones can cause other common symptoms of perimenopause and menopause, such as disturbed sleep and hot flushes. Some women experience bothersome symptoms that significantly impact their quality of life. Sleep disturbances are common among menopausal women, often including trouble falling asleep and waking up several times during the night. For a more in-depth look at the symptoms, see our Symptomschecklist here..

When progesterone is low compared to estrogen this can cause very heavy or painful periods. This is because estrogen thickens the uterus lining, while progesterone thins it.

When estrogen levels are low or dropping rapidly as you come into menopause (when you don’t have a period for 12 consecutive months) you might experience hot flushes and night sweats, the vasomotor symptoms related to the constriction and dilation of blood vessels. These are considered disruptive symptoms that can interfere with daily activities and sleep. Identifying and avoiding triggers for hot flashes can help relieve these symptoms.

When estrogen levels have been low for some time, it is common to experience dry skin and eyes, as well as dryness of the vaginal tissue, which for some women can make sex quite uncomfortable, even at times painful. Urinary symptoms, such as increased frequency or urgency, can also occur due to changes in the bladder and urethra.

Testosterone plays an important role in muscle mass, bone strength, cardiovascular health, cognitive performance, and overall energy levels, while also influencing libido and sexual pleasure. So as testosterone levels decline, many women experience fatigue, brain fog, and decreased sexual desire, regardless of their emotional connection with their partner.

Bone loss accelerates after menopause due to declining estrogen, increasing the risk of osteoporosis. The importance of bone health during and after menopause cannot be overstated, and strategies such as weight-bearing exercise, adequate calcium and vitamin D intake, and sometimes hormone therapy can help maintain it.

As women have reached menopause, it is important to be aware of risk factors for long-term health issues, such as osteoporosis and cardiovascular disease, and to take preventive measures. Menopause can affect various aspects of health, including sexual activity and libido, potentially influencing intimacy and relationships.

Understanding Postmenopause: What to Expect and How to Support Your Health

Postmenopause is the final stage of the menopause journey, and officially begins 12 months after your final period (themenopause). During postmenopause, your body continues to produce testosterone and estrogen, although in smaller amounts. The production of progesterone stops because it is made by the ovaries after ovulation, which stops at menopause.

Hormones stabilise at lower levels after menopause, although some symptoms may persist for a while as your body adjusts. For most women, symptoms start to become less troublesome, even disappearing altogether.

At any stage of your menopause journey, if symptoms are interfering with your quality of life, it's worth discussing the pros and cons of medications with your doctor, as well as considering dietary changes, exercise, weight management, and permiumsupplements, which all play an important role in our overall health. Regular physical activity can also help alleviate several menopause symptoms.

 

Discoverour range of evidence-based supplements,developed with mind and body nutrientsto support your body and your needs before, during, and after this transitionary life stage.

Thisarticle has been reviewed byour expert advisory team.

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